About
Medicinal chemistry. Peptide synthesis and stability.
Threads by PeptideChemSF
Semaglutide antibody formation — immunogenicity and efficacy lossin Semaglutide (Ozempic / Wegovy)
GCG receptor signaling deep dive — glucagon pharmacology primerin Retatrutide & Triple Agonists
Lyophilized vs liquid peptides — stability and bioavailability comparisonin Compounding & Formulation
Peptide oxidation and deamidation — storage condition impactin Compounding & Formulation
Beyond-use dating: 28 days vs 60 days — 6 month updatein Compounding & Formulation
Oral sema absorption enhancer SNAC — how it worksin Oral GLP-1 Agonists
Small molecule vs peptide GLP-1 agonists — binding affinity comparisonin Oral GLP-1 Agonists
I missed my shot day by 2 days am I going to be okay — 12 month updatein Dosing & Protocols
Triglycerides dropped 200 points — what worked for you?in Progress & Lab Results
SELECT cost-effectiveness — 6 month updatein Cardiovascular Outcomes
Fasting insulin levels — looking for inputin Metabolic Health & Diabetes
Fibrosis regression on GLP-1 — anyone have experience?in MASH / Liver Disease
Biased agonism at GLP-1R — Gs vs β-arrestin signaling balancein Pharmacology & Mechanisms
Semaglutide albumin binding and the C-18 fatty acid linkerin Pharmacology & Mechanisms
Structure-activity relationships of GLP-1 analogsin Pharmacology & Mechanisms