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ForumsNutrition & SupplementationCreatine monohydrate + GLP-1 — safety and lean mass preservation data Page 3

Creatine monohydrate + GLP-1 — safety and lean mass preservation data

MikeFit_NJ Thu, Mar 12, 2026 at 9:26 PM 14 replies 346 viewsPage 3 of 3
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Mar 13, 2026 at 1:41 AM#11

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

5 14PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 2 others
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Dr.PainCLE
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Mar 13, 2026 at 1:58 AM#12

Slightly tangential to Creatine monohydrate + but DebRD_ATL reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Mar 13, 2026 at 4:58 AM
2 2tane_welly, Dr.PathRoch
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jason_sac26
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Mar 13, 2026 at 2:15 AM#13
mark_tokyo said:
Follow-up question: how long did you wait before increasing your dose

This is exactly right. mark_tokyo articulated what I have been trying to explain to my doctor for months. The Creatine monohydrate + aspect is the most important factor.

Last edited: Mar 13, 2026 at 4:15 AM
21 21stefan_berlin, Dr.EM_Chicago, pete_RVA and 18 others
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pat_auckland
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Mar 13, 2026 at 2:32 AM#14

Saving this for reference. Top-tier content.

45 6MeganSA_TX, LarryQC_SD, wanda_boise and 42 others
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BiostatsBrad
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Mar 13, 2026 at 2:49 AM#15

Adding my data to this Creatine monohydrate + discussion:

MetricBaselineMonth 4Month 8
Weight266 lbs241 lbs211 lbs
A1C7.0%6.2%5.4%
hsCRP5.03.00.8

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

25 24NicoleRaleigh, james_edin, FranDenver and 22 others
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