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ForumsNutrition & SupplementationCreatine monohydrate + GLP-1 — looking for input Page 2

Creatine monohydrate + GLP-1 — looking for input

hyun_seoul Thu, Dec 18, 2025 at 10:11 AM 31 replies 1,267 viewsPage 2 of 7
maya_sedona
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Sep 2024
Sedona, AZ
Dec 18, 2025 at 1:01 PM#6

Okay the water retention thing is what scares me. I weigh myself daily (I know, I know) and seeing the scale go UP would honestly send me into a spiral. My brain knows it's water but my anxiety doesn't care.

Anyone have tips for mentally handling that initial scale bump? Or should I just not weigh myself for 2 weeks when I start?

44 14wanda_boise, NurseAsh_DET, BenResearch_OR and 41 others
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Dr.RaviCardio
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Jan 2024
New York, NY
Dec 18, 2025 at 1:18 PM#7

Honestly? Don't weigh yourself for 3 weeks when you start creatine. Or switch to weekly weigh-ins using a rolling average. The day-to-day fluctuations on creatine + GLP-1 + normal water/food variation can be like 2-3kg in either direction on any given day. It'll drive you nuts.

Better metrics while on creatine: waist circumference, how clothes fit, progress photos, lifting numbers. The scale becomes a less useful tool (it was never a great one honestly).

26 9anna.melb_AU, mark_tokyo, hans_munich and 23 others
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maria_elpaso
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Sep 2024
El Paso, TX
Dec 18, 2025 at 1:35 PM#8

I'll play devil's advocate slightly. While creatine is safe and well-studied, I think the GLP-1 community sometimes treats it as a magic bullet for muscle preservation. It helps, yes, but the effect size is modest. The hierarchy should be:

  1. Adequate protein intake (1.2-1.6g/kg) — biggest impact
  2. Consistent resistance training with progressive overload — second biggest
  3. Adequate sleep (7-9 hrs) — often overlooked, hugely important
  4. Creatine 5g/day — helpful but marginal compared to the above

Don't add creatine while eating 60g protein and doing no exercise. Fix the foundations first.

17 21TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 14 others
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wei_SG
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Nov 2024
Singapore, SG
Dec 18, 2025 at 1:52 PM#9

Totally fair hierarchy. Creatine is the cherry on top, not the cake itself. Thanks everyone for the thorough discussion — this is exactly the kind of evidence-based conversation I was hoping for. Starting 5g/day tomorrow, no loading phase, with breakfast. Will report back in a month. 💊🏋️

Last edited: Dec 18, 2025 at 2:52 PM
8 7RetaRick_CA, JenPlateau, SallyK_inj and 5 others
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