VendorMark said:

3%, triglycerides 191 → 91 mg/dL, hsCRP 6

This is exactly right. VendorMark articulated what I have been trying to explain to my friends for months. The Chemyo international aspect is what made the difference for me.

Relevant to Chemyo international shipping — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 199 → 99 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Thank you BrianDallas92! This is incredibly helpful. Bookmarking for later. 🙏

SkepticalSean — that is really helpful context on Chemyo international. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

To answer marco_milano's question specifically:

From a clinical standpoint, Chemyo international shipping is something I discuss with patients regularly.

The short answer: discuss this specific situation with your prescribing provider.

The longer answer involves weighing the risk-benefit ratio for your individual situation, which I am happy to elaborate on if helpful.