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Evidence-based GLP-1 & peptide discussion since 2023
ForumsNutrition & SupplementationOmega-3 supplementation — what worked for you? Page 5

Omega-3 supplementation — what worked for you?

Dr.LeslieOBGYN Wed, Oct 15, 2025 at 2:45 AM 29 replies 1,541 viewsPage 5 of 6
fiona_VT
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Vermont
Oct 15, 2025 at 9:50 AM#21

Congrats Dr.LeslieOBGYN!! You should be so proud of yourself. 🎉

19 7mark_tokyo, hans_munich, jason_sac26 and 16 others
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NeuroNate
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Chicago, IL
Oct 15, 2025 at 10:07 AM#22

Reading this thread on Omega-3 supplementation hits close to home. Dad of 2 checking in — I started at 289 lbs and felt like I would tried everything.

15 months on tirz and I am a different person. Not just the 64 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Omega-3 supplementat — take the leap. It was the best health decision I have ever made. ❤️

3 20wendy_avl, jason_paloalto, Dr.LeslieOBGYN
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GenomicsKate
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Oct 2024
Cambridge, MA
Oct 15, 2025 at 10:24 AM#23

As a healthcare provider, I want to add some clinical context to this discussion on Omega-3 supplementation what worked for.

Building on what fiona_VT said — the evidence base here is well-established. The key publications to reference are from the STEP program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
7 11MarkLI_maint, Dr.PeteFamMed, claudia_zurich and 4 others
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amy_econ_NJ
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Oct 15, 2025 at 10:41 AM#24

NeuroNate — wow. This community is amazing.

25 13gary_naperville, sean_dublin, hannah_MT and 22 others
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bri_stats
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Seattle, WA
Oct 15, 2025 at 10:58 AM#25

Adding my data to this Omega-3 supplementation discussion:

MetricBaselineMonth 5Month 8
Weight242 lbs247 lbs197 lbs
A1C6.6%6.0%5.4%
hsCRP6.04.00.8

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.

2 1julia.endo, JessicaM_2024
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