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Evidence-based GLP-1 & peptide discussion since 2023
ForumsNutrition & SupplementationMagnesium supplementation on GLP-1 — looking for input Page 5

Magnesium supplementation on GLP-1 — looking for input

Dr.DermMIA Sun, Mar 9, 2025 at 9:11 AM 41 replies 2,144 viewsPage 5 of 9
PurityPaulOR
Senior Member
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Oregon
Mar 9, 2025 at 4:16 PM#21

Congrats Dr.DermMIA!! You should be so proud of yourself. 🎉

7 5Dr.LeslieOBGYN, MikeNYC_runner and 4 others
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FitDadDave
Member
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Jul 2024
Minneapolis, MN
Mar 9, 2025 at 4:33 PM#22

Reading this thread on Magnesium supplementation hits close to home. Dad of 2 checking in — I started at 269 lbs and felt like I would tried everything.

15 months on tirz and I am a different person. Not just the 44 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Magnesium supplement — take the leap. It was the best health decision I have ever made. ❤️

33 2kim_atl_prep, sarah_TO, wendy_avl and 30 others
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CarlaRPh_TPA
Senior Member
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Jan 2024
Tampa, FL
Mar 9, 2025 at 4:50 PM#23

As a healthcare provider, I want to add some clinical context to this discussion on Magnesium supplementation on GLP-1 .

Building on what PurityPaulOR said — the evidence base here is well-established. The key publications to reference are from the STEP program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
27 21BrianDallas92, labquiet_amy, emily_PDX and 24 others
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anna.melb_AU
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Apr 2024
Melbourne, AU
Mar 9, 2025 at 5:07 PM#24

FitDadDave — wow. This community is amazing.

41 10tammy_FL, Dr.LipidDallas, alex_tucson and 38 others
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NicoleRaleigh
Member
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Aug 2024
Raleigh, NC
Mar 9, 2025 at 5:24 PM#25

Adding my data to this Magnesium supplementation discussion:

MetricBaselineMonth 5Month 8
Weight262 lbs222 lbs197 lbs
A1C6.6%6.0%5.4%
hsCRP6.04.01.2

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.

29 7mike_nyc, VendorMark, COA_Karl and 26 others
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