Relevant to Semaglutide titration — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 237 → 107 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Want to share my personal experience related to Semaglutide titration since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 278 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 18 months later: I am down 63 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Semaglutide aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

PharmacoVig_BOS — that is really helpful context on Semaglutide titration. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

Want to share my personal experience related to Semaglutide titration since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 250 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 10 months later: I am down 70 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Semaglutide aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

PharmacoVig_BOS — that is really helpful context on Semaglutide titration. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.