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ForumsDosing & ProtocolsMicro-dosing semaglutide — is sub-therapeutic dosing effective? Page 4

Micro-dosing semaglutide — is sub-therapeutic dosing effective?

Dr.ObesityMed Fri, Mar 13, 2026 at 12:53 AM 16 replies 160 viewsPage 4 of 4
Dr.ObesityMed
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Mar 13, 2026 at 6:33 AM#16

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Micro-dosing semaglutide .

To answer sean_dublin: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Mar 13, 2026 at 12:33 PM
9 22EndoResFellow, PharmacoVig_BOS, SurmountFan_IN and 6 others
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Dr.PathRoch
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Mar 13, 2026 at 6:50 AM#17

Adding my data to this Micro-dosing semaglutide discussion:

MetricBaselineMonth 3Month 8
Weight250 lbs215 lbs195 lbs
A1C6.4%5.8%5.4%
hsCRP4.02.00.8

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.

38 5InsuranceTom, WendyG_ATL, SaraMom3 and 35 others
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AttorneyGrant
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Mar 13, 2026 at 7:07 AM#18

Agreed. My doctor said the same thing about Micro-dosing.

6 4JenMemphis, pat_auckland, Dr.GastroMayo and 3 others
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CarlaRPh_TPA
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Mar 13, 2026 at 7:24 AM#19

Slightly tangential to Micro-dosing semaglutide but adam_van reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

22 10labquiet_amy, emily_PDX, Dr.SleepRoch and 19 others
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Dr.EndoIndy
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Mar 13, 2026 at 7:41 AM#20

+1 to Dr.ObesityMed. Especially the point about "Thank you all for the thoughtful replies..." — I have seen the same in my own experience with Micro-dosing semaglutide .

35 6SandraNC_45, Dr.EndoIndy, tom_AK and 32 others
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