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Tagging this for the weekly digest. 👍
Slightly tangential to Semaglutide PK modeling but PharmacoVig_BOS reminded me — does anyone have experience combining this with metformin?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
MikeKY_noInsulin said:Follow-up question: how long did you wait before increasing your dose
This is exactly right. MikeKY_noInsulin articulated what I have been trying to explain to my doctor for months. The Semaglutide PK modeling aspect is the most important factor.
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View ResultsSaving this for reference. Top-tier content.
Adding my data to this Semaglutide PK modeling discussion:
| Metric | Baseline | Month 5 | Month 8 |
|---|---|---|---|
| Weight | 270 lbs | 225 lbs | 215 lbs |
| A1C | 6.4% | 6.0% | 5.4% |
| hsCRP | 4.0 | 4.0 | 1.2 |
Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.