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Evidence-based GLP-1 & peptide discussion since 2023
ForumsBuyer Beware⚠ Buyer Beware posting rules — read before posting Page 5

⚠ Buyer Beware posting rules — read before posting

Admin Fri, Dec 1, 2023 at 4:00 PM 518 replies 47,405 viewsPage 5 of 20
JakeSmashed95
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Dec 1, 2023 at 11:05 PM#21

SarahChen_PharmD — that is really helpful context on Buyer Beware posting. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

Last edited: Dec 2, 2023 at 4:05 AM
1 4Dr.PainCLE
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Dr.LipidDallas
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Dec 1, 2023 at 11:22 PM#22

To answer FranDenver's question specifically:

From a clinical standpoint, Buyer Beware posting rules is well-supported by the literature.

The short answer: follow the standard titration protocol and reassess at 4-6 weeks.

The longer answer involves pharmacokinetic considerations around steady-state concentrations, which I am happy to elaborate on if helpful.

14 12wei_SG, cory_ATX, lori_vegas and 11 others
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NeuroNate
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Dec 1, 2023 at 11:39 PM#23

JakeSmashed95 — wow. This community is amazing.

14 23sarah_TO, wendy_avl, jason_paloalto and 11 others
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FDA_TrackerJim
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Dec 1, 2023 at 11:56 PM#24

Adding my data to this Buyer Beware posting discussion:

MetricBaselineMonth 5Month 8
Weight250 lbs245 lbs215 lbs
A1C6.4%6.0%5.4%
hsCRP4.04.00.8

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.

Last edited: Dec 2, 2023 at 2:56 AM
28 6Dr.LeslieOBGYN, MikeNYC_runner and 25 others
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PeptideSynthNJ
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Dec 2, 2023 at 12:13 AM#25

Slightly tangential to Buyer Beware posting but JakeSmashed95 reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Dec 2, 2023 at 4:13 AM
13 16Dr.RaviCardio, jennifer_SEA, tyler_CSCS and 10 others
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