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Evidence-based GLP-1 & peptide discussion since 2023
ForumsDosing & ProtocolsTirzepatide titration: 2.5→5→7.5→10→12.5→15mg guide Page 11

Tirzepatide titration: 2.5→5→7.5→10→12.5→15mg guide

Dr.Martinez Fri, Nov 24, 2023 at 5:20 PM 72 replies 44,284 viewsPage 11 of 15
Dr.Martinez
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Nov 25, 2023 at 8:55 AM#51

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Tirzepatide titration.

To answer Dr.Martinez: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

20 15AttorneyGrant, DebRD_ATL, KristenIndy and 17 others
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fiona_glasgow
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Nov 25, 2023 at 9:12 AM#52

Slightly tangential to Tirzepatide titration but PharmHunterJen reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

16 22TirzTom, TrialTracker_MD, JennaRN and 13 others
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carlos_SATX
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Nov 25, 2023 at 9:29 AM#53

Saving this for reference. Quality thread.

Last edited: Nov 25, 2023 at 11:29 AM
42 15Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 39 others
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LabKate
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Nov 25, 2023 at 9:46 AM#54

Slightly tangential to Tirzepatide titration but PharmHunterJen reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Nov 25, 2023 at 12:46 PM
41 6emily_PDX, Dr.SleepRoch, laura_annarbor and 38 others
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labquiet_amy
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Nov 25, 2023 at 10:03 AM#55

Relevant to Tirzepatide titration — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 205 → 105 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Nov 25, 2023 at 12:03 PM
41 3pete_manc_UK, anna.melb_AU, mark_tokyo and 38 others
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