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ForumsDosing & ProtocolsTirzepatide titration: 2.5→5→7.5→10→12.5→15mg guide Page 12

Tirzepatide titration: 2.5→5→7.5→10→12.5→15mg guide

Dr.Martinez Fri, Nov 24, 2023 at 5:20 PM 72 replies 44,284 viewsPage 12 of 15
TomFromTexas
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May 2024
Austin, TX
Nov 25, 2023 at 10:20 AM#56

Want to share my personal experience related to Tirzepatide titration since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 276 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 8 months later: I am down 46 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Tirzepatide aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Last edited: Nov 25, 2023 at 12:20 PM
47 24PharmD_Rodriguez, julia.endo, JessicaM_2024 and 44 others
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SallyK_inj
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567
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Jul 2024
Iowa
Nov 25, 2023 at 10:37 AM#57

labquiet_amy — that is really helpful context on Tirzepatide titration. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

Last edited: Nov 25, 2023 at 11:37 AM
31 5bbq_ray_KC, oliver_london, tane_welly and 28 others
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matt_MKE
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312
1,345
Sep 2024
Milwaukee, WI
Nov 25, 2023 at 10:54 AM#58

Want to share my personal experience related to Tirzepatide titration since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 248 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 14 months later: I am down 53 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Tirzepatide aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

15 16GraceAZ_72, carl_compliance, DanielChem_CHI and 12 others
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CanadaChris
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Nov 2024
Toronto, CA
Nov 25, 2023 at 11:11 AM#59

labquiet_amy — that is really helpful context on Tirzepatide titration. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

30 11Dr.PulmRoch, maya_sedona, stefan_berlin and 27 others
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mel_PDX
Member
189
890
Dec 2024
Portland, OR
Nov 25, 2023 at 11:28 AM#60

Want to share my personal experience related to Tirzepatide titration since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 265 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 6 months later: I am down 60 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Tirzepatide aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Last edited: Nov 25, 2023 at 5:28 PM
49 8RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 46 others
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