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ForumsDosing & ProtocolsWeekend vs weekday injection — does timing of dose day matter? Page 3

Weekend vs weekday injection — does timing of dose day matter?

matt_MKE Wed, Feb 25, 2026 at 11:12 PM 11 replies 508 viewsPage 3 of 3
Dr.BariatricHTX
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Feb 26, 2026 at 3:27 AM#11

Bookmarked 📌 The Weekend vs weekday info in this thread is essential. Coming back to this for sure.

10 24CarlaRPh_TPA, steph_laguna, fiona_glasgow and 7 others
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anders_CPH
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Feb 26, 2026 at 3:44 AM#12

Relevant to Weekend vs weekday injection — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 237 → 107 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Feb 26, 2026 at 7:44 AM
44 16MariaRD, AussieAnna, BethLabQueen and 41 others
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Admin
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Feb 26, 2026 at 4:01 AM#13

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

28 18RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 25 others
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JennaRN
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Feb 26, 2026 at 4:18 AM#14

+1 to PeptideChemSF. Especially the point about "For Weekend vs weekday injection does, ..." — I have seen the same in my own experience with Weekend vs weekday.

Last edited: Feb 26, 2026 at 5:18 AM
24 4RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 21 others
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matt_MKE
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Feb 26, 2026 at 4:35 AM#15

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Weekend vs weekday.

To answer matt_MKE: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

23 15DanielChem_CHI, marco_milano, pam_columbus and 20 others
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