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Evidence-based GLP-1 & peptide discussion since 2023
Forumsβ€ΊDosing & Protocolsβ€ΊI missed my shot day by 2 days am I going to be okay

I missed my shot day by 2 days am I going to be okay

tammy_FL Thu, Feb 5, 2026 at 11:41 PM 10 replies 580 viewsPage 1 of 2
tammy_FL
Member
234
890
Nov 2024
Tampa, FL
Feb 6, 2026 at 1:06 AM#1

Can I just vent for a second about i missed my shot day by?

I know this forum is evidence-based and I love that about it, but sometimes you just need to let it out. I hit another plateau and I am frustrated.

Not looking for a fix necessarily β€” just solidarity. Anyone else going through this right now?

39 11Dr.LipidDallas, alex_tucson, kevin_tulsa and 36 others
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TrialNerd_Beth
Senior Member
2,345
11,234
Jan 2024
Bethesda, MD
Feb 6, 2026 at 1:23 AM#2

tammy_FL's experience with I missed my shot day by 2 resonates deeply with mine. I went through almost the identical process β€” starting dose, titration timeline, side effects, everything.

The main difference: I titrated faster. But the overall trajectory has been remarkably similar. Down 44 lbs in 9 months.

One thing I would add that tammy_FL did not mention: the relationship with food fundamentally changed.

Last edited: Feb 6, 2026 at 5:23 AM
4 15PharmHunterJen, TomTeleRx, DoseLogDan and 1 other
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GenomicsKate
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Oct 2024
Cambridge, MA
Feb 6, 2026 at 1:40 AM#3

Thanks for sharing this, tammy_FL. A few questions about your I missed my shot day experience:

  1. What dose worked best for you?
  2. How long before you noticed appetite suppression kicking in?
  3. Did your endo have any specific recommendations about I missed my?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Feb 6, 2026 at 6:40 AM
14 1MarkLI_maint, Dr.PeteFamMed, claudia_zurich and 11 others
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tammy_FL
Member
234
890
Nov 2024
Tampa, FL
Feb 6, 2026 at 1:57 AM#4

OP here β€” wow, did not expect this much response! Thank you all for the thoughtful replies on I missed my shot day by 2.

To answer GenomicsKate: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion β€” this is exactly why I posted in a science-based community. πŸ™

Last edited: Feb 6, 2026 at 7:57 AM
5 21Dr.PainCLE, mike_mealprep, NicoleRaleigh and 2 others
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Dr.GutHealth
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Mar 2024
Minnesota
Feb 6, 2026 at 2:14 AM#5

Relevant to I missed my shot day by 2 days β€” here is my latest bloodwork comparison:

Key improvements: A1C 7.6% β†’ 5.5%, triglycerides 197 β†’ 97 mg/dL, hsCRP 8.0 β†’ 0.9 mg/L. All on tirzepatide for 13 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

37 19MikeKY_noInsulin, Dr.RaviCardio, jennifer_SEA and 34 others
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