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Forumsβ€ΊDosing & Protocolsβ€ΊMy doctor says stay on 1mg but I feel like I need more

My doctor says stay on 1mg but I feel like I need more

JenPlateau Fri, Jan 30, 2026 at 5:57 PM 26 replies 745 viewsPage 1 of 6
JenPlateau
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Nov 2024
Missouri
Jan 30, 2026 at 7:22 PM#1

Okay I need help with this β€” my doctor says stay on 1mg.

I have been dealing with this for way too long and I am getting frustrated. Googling just gives me contradictory information and my endo does not seem to take it seriously.

Please tell me someone here has been through this and come out the other side. What did you do? What finally worked?

I know there are some really knowledgeable people on this forum so I am hoping someone can point me in the right direction. 😩

30 17HPLC_Greg, LibrarianMeg, bri_stats and 27 others
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CarlaRPh_TPA
Senior Member
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Jan 2024
Tampa, FL
Jan 30, 2026 at 7:39 PM#2

JenPlateau's experience with My doctor says stay on resonates deeply with mine. I went through almost the identical process β€” starting dose, titration timeline, side effects, everything.

The main difference: I started 3 months later. But the overall trajectory has been remarkably similar. Down 46 lbs in 11 months.

One thing I would add that JenPlateau did not mention: the mental health improvements were just as significant.

11 18ricardo_MIA, BrianDallas92, labquiet_amy and 8 others
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AmyNC_wife
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Jun 2024
North Carolina
Jan 30, 2026 at 7:56 PM#3

Thanks for sharing this, JenPlateau. A few questions about your My doctor says stay experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about My doctor says?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Jan 30, 2026 at 8:56 PM
34 7PharmD_Rodriguez, julia.endo, JessicaM_2024 and 31 others
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JenPlateau
Member
234
890
Nov 2024
Missouri
Jan 30, 2026 at 8:13 PM#4

OP here β€” wow, did not expect this much response! Thank you all for the thoughtful replies on My doctor says stay on.

To answer AmyNC_wife: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion β€” this is exactly why I posted in a science-based community. πŸ™

34 23FitDadDave, RunnerRach, TrialNerd_Beth and 31 others
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PharmacoVig_BOS
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Feb 2024
Boston, MA
Jan 30, 2026 at 8:30 PM#5

Relevant to My doctor says stay on 1mg but β€” here is my latest bloodwork comparison:

Key improvements: A1C 8.0% β†’ 5.3%, triglycerides 219 β†’ 119 mg/dL, hsCRP 6.0 β†’ 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Jan 30, 2026 at 11:30 PM
12 24LabKate, kate.chem, DataDave and 9 others
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