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International vendor directory — need advice

jason_sac26 Tue, Jan 20, 2026 at 7:40 AM 37 replies 1,223 viewsPage 6 of 8
BariatricNurseD
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Jan 20, 2026 at 4:10 PM#26

Congrats jason_sac26!! You should be so proud of yourself. 🎉

15 0tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 12 others
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Dr.GutHealth
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Jan 20, 2026 at 4:27 PM#27

Slightly tangential to International vendor but Admin reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

10 9tyler_CSCS, VanRx_Mike, steve_okc and 7 others
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Dr.LipidDallas
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Jan 20, 2026 at 4:44 PM#28

Yep. My endo said the same thing about International vendor.

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Dr.NutriCornell
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Ithaca, NY
Jan 20, 2026 at 5:01 PM#29

Reading this thread on International vendor hits close to home. Night shift nurse — I started at 295 lbs and felt like I would tried everything.

11 months on tirz and I am a different person. Not just the 70 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about International vendor — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Jan 20, 2026 at 7:01 PM
27 23JenMemphis, pat_auckland, Dr.GastroMayo and 24 others
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newstart_MO
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Jan 20, 2026 at 5:18 PM#30

As a pharmacist, I want to add some clinical context to this discussion on International vendor directory need.

Building on what Dr.LipidDallas said — the evidence base here is robust. The key publications to reference are from the SURMOUNT program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
9 19RunnerRach, TrialNerd_Beth, HPLC_Greg and 6 others
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