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ForumsDosing & ProtocolsCompounded sema dosing calculator — 12 month update Page 2

Compounded sema dosing calculator — 12 month update

CarlaRPh_TPA Thu, Dec 18, 2025 at 12:53 PM 27 replies 1,129 viewsPage 2 of 6
LabKate
Senior Member
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Jan 2024
Oregon
Dec 18, 2025 at 3:43 PM#6

Quick practical note — if you're doing 0.125mg from a compounded vial, the reconstitution math matters a lot here. With a 5mg vial:

  • Add 2mL BAC water → 2.5mg/mL → 0.125mg = 0.05mL = 5 units

5 units on an insulin syringe is a very small amount — just be sure you're using a syringe with fine enough markings. A 0.3mL (30-unit) syringe will have individual unit markings and be much easier to read accurately at this volume than a full 1mL syringe.

6 11JenMemphis, pat_auckland, Dr.GastroMayo and 3 others
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LindaRN_retired
Member
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Dec 2024
Sarasota, FL
Dec 18, 2025 at 4:00 PM#7

Great call on the syringe. I'll order the 0.3mL ones. Thank you for the advice! 🙏

Last edited: Dec 18, 2025 at 7:00 PM
16 21Dr.GutHealth, amsterdam_pete, LondonLisa and 13 others
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jennifer_SEA
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Nov 2024
Seattle, WA
Dec 18, 2025 at 4:17 PM#8

Good discussion. I'll just add the standard disclaimer that micro-dosing is off-label and should be done under provider supervision. We don't want anyone reading this thread and deciding to start at a random low dose without medical guidance. Your provider can factor in your full medical history, not just your weight.

7 1matt_MKE, Dr.ReproEndo, lucas_SP_BR and 4 others
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