+1. This mirrors my journey exactly. The Compounded sema discussion here is so valuable.

Dr.SurgeonPGH said:

Dad of 2 checking in — I started at 277 lbs and felt like I would tried everything

I respect Dr.SurgeonPGH perspective but I think this oversimplifies things a bit. Re: Compounded sema dosing — the subgroup analyses show meaningful heterogeneity.

I am not saying Dr.SurgeonPGH wrong entirely — just that the picture is more nuanced than a blanket statement. The SURMOUNT data specifically shows baseline BMI-dependent responses.

Reading this thread on Compounded sema dosing hits close to home. Night shift nurse — I started at 263 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 38 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Compounded sema — take the leap. It was the best health decision I have ever made. ❤️

Bookmarked 📌 The Compounded sema info in this thread is essential. Coming back to this for sure.

nick_newbie — that is really helpful context on Compounded sema dosing. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.