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ForumsDosing & ProtocolsWeekend vs weekday injection — 12 month update Page 6

Weekend vs weekday injection — 12 month update

Admin Fri, Nov 7, 2025 at 3:42 PM 37 replies 1,305 viewsPage 6 of 8
TirzTom
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Nov 8, 2025 at 12:12 AM#26

Following this thread closely. Weekend vs weekday is something I'm actively working through.

14 18josh_phd_bmore, roxy_nash, tony_orlando and 11 others
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HPLC_Greg
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Nov 8, 2025 at 12:29 AM#27
BenResearch_OR said:
Night shift nurse — I started at 283 lbs and felt like I would tried everything

I respect BenResearch_OR perspective but I think this oversimplifies things a bit. Re: Weekend vs weekday injection — the effect size varies considerably by population.

I am not saying BenResearch_OR wrong entirely — just that the picture is more nuanced than a blanket statement. The SURMOUNT data specifically shows baseline BMI-dependent responses.

20 20JenPlateau, SallyK_inj, CryptoCarl and 17 others
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julia.endo
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Nov 8, 2025 at 12:46 AM#28

Reading this thread on Weekend vs weekday hits close to home. Dad of 2 checking in — I started at 269 lbs and felt like I would tried everything.

15 months on tirz and I am a different person. Not just the 44 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Weekend vs weekday — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Nov 8, 2025 at 6:46 AM
22 8hans_munich, jason_sac26, chris_chi24 and 19 others
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jennifer_SEA
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Nov 8, 2025 at 1:03 AM#29

Bookmarked 📌 The Weekend vs weekday info in this thread is essential. Coming back to this for sure.

19 14jim_asheville, matt_MKE, Dr.ReproEndo and 16 others
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pete_nash
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Nov 8, 2025 at 1:20 AM#30

TirzTom — that is really helpful context on Weekend vs weekday. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

19 15sarah.morrison, NeuroNate, JessicaH_TX and 16 others
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