Oct 15, 2025 at 11:07 AM#16
Congrats fiona_VT!! You should be so proud of yourself. 🎉
9 19Dr.PainCLE, mike_mealprep, NicoleRaleigh and 6 others
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Oct 15, 2025 at 11:24 AM#17
CryptoCarl's experience with PK/PD modeling for resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.
The main difference: I am on a different medication. But the overall trajectory has been remarkably similar. Down 51 lbs in 6 months.
One thing I would add that CryptoCarl did not mention: my sleep quality improved dramatically.
37 14JessicaM_2024, TomFromTexas, mike.trainer_LA and 34 others
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Oct 15, 2025 at 11:41 AM#18
Bookmarked 📌 The PK/PD modeling for info in this thread is essential. Coming back to this for sure.
Last edited: Oct 15, 2025 at 5:41 PM
40 4BrianDallas92, labquiet_amy, emily_PDX and 37 others
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View ResultsOct 15, 2025 at 11:58 AM#19
Clinical perspective on PK/PD modeling for tirzepatide anyone:
I have managed over 200 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.
For this specific question, I would recommend: reviewing the relevant clinical guidelines.
34 4julia.endo, JessicaM_2024, TomFromTexas and 31 others
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Oct 15, 2025 at 12:15 PM#20
Subscribing to this thread. PK/PD modeling for is exactly what I've been researching. 🙏
19 10lisa_labSD, adam_van, Dr.SurgeonPGH and 16 others
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