🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsPharmacology & MechanismsSo the drug literally changes your brain?? That is wild Page 2

So the drug literally changes your brain?? That is wild

tammy_FL Tue, Feb 17, 2026 at 2:08 AM 26 replies 905 viewsPage 2 of 6
TinaHashiRN
Member
345
1,567
Sep 2024
Raleigh, NC
Feb 17, 2026 at 4:58 AM#6

Subscribing to this thread. So the drug literally is exactly what I've been researching. 🙏

Last edited: Feb 17, 2026 at 10:58 AM
43 12SarahChen_PharmD, sarah.morrison, NeuroNate and 40 others
Reply Quote Save Share Report
tammy_FL
Member
234
890
Nov 2024
Tampa, FL
Feb 17, 2026 at 5:15 AM#7

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on So the drug literally.

To answer KevinCompounds: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

18 11alex_tucson, kevin_tulsa, Dr.PainCLE and 15 others
Reply Quote Save Share Report
DoseLogDan
Member
201
567
Feb 2025
Montana
Feb 17, 2026 at 5:32 AM#8

Adding my data to this So the drug literally discussion:

MetricBaselineMonth 4Month 8
Weight270 lbs240 lbs205 lbs
A1C6.4%6.2%5.4%
hsCRP4.03.01.2

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.

Last edited: Feb 17, 2026 at 6:32 AM
1 12mel_PDX
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides
AussieAnna
Member
678
2,890
Jun 2024
Sydney, AU
Feb 17, 2026 at 5:49 AM#9

+1 to tammy_FL. Especially the point about "Thank you all for the thoughtful replies..." — I have seen the same in my own experience with So the drug literally.

21 3bri_stats, pete_manc_UK, anna.melb_AU and 18 others
Reply Quote Save Share Report
Dr.DermMIA
Member
456
2,123
May 2024
Miami, FL
Feb 17, 2026 at 6:06 AM#10

Slightly tangential to So the drug literally but hyun_seoul reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Feb 17, 2026 at 8:06 AM
1 11SurmountFan_IN
Reply Quote Save Share Report

Similar Threads

GLP-1R desensitization — β-arrestin-mediated internalization18 replies
Biased agonism at GLP-1R — Gs vs β-arrestin signaling balance13 replies
Semaglutide albumin binding and the C-18 fatty acid linker17 replies
GIP receptor pharmacology — why GIP agonism enhances GLP-113 replies
Glucagon receptor signaling — hepatic glycogenolysis and lipolysis16 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register