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ForumsPharmacology & MechanismsSo the drug literally changes your brain?? That is wild Page 5

So the drug literally changes your brain?? That is wild

tammy_FL Tue, Feb 17, 2026 at 2:08 AM 26 replies 905 viewsPage 5 of 6
dan_philly
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Jul 2024
Philadelphia, PA
Feb 17, 2026 at 9:13 AM#21

Relevant to So the drug literally changes — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 243 → 113 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

1 19DadBodDave
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LindaRN_retired
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189
890
Dec 2024
Sarasota, FL
Feb 17, 2026 at 9:30 AM#22

Want to share my personal experience related to So the drug literally changes since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 254 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 10 months later: I am down 69 lbs, my labs have normalized, and I am off 2 of my 3 medications. The So the drug aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

13 0Dr.GutHealth, amsterdam_pete, LondonLisa and 10 others
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MounjBrad
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Oct 2024
Kentucky
Feb 17, 2026 at 9:47 AM#23

SteveThurs — that is really helpful context on So the drug literally. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

17 15nick_SD_fit, ben_calgary, patPC_UT and 14 others
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pete_nash
Member
312
1,345
Aug 2024
Nashville, TN
Feb 17, 2026 at 10:04 AM#24

Want to share my personal experience related to So the drug literally changes since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 271 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 16 months later: I am down 76 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The So the drug aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

42 8SarahChen_PharmD, sarah.morrison, NeuroNate and 39 others
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GraceAZ_72
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156
678
Jan 2025
Tucson, AZ
Feb 17, 2026 at 10:21 AM#25

MounjBrad — that is really helpful context on So the drug literally. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

46 15RetaRick_CA, JenPlateau, SallyK_inj and 43 others
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