Mar 11, 2026 at 11:53 PM#6
+1. This mirrors my journey exactly. The GLP-1 and beta-cell discussion here is so valuable.
Last edited: Mar 12, 2026 at 2:53 AM
28 5NeuroNate, JessicaH_TX, KevinCompounds and 25 others
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Mar 12, 2026 at 12:10 AM#7
OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on GLP-1 and beta-cell.
To answer RetaRick_CA: I started tracking everything in a spreadsheet from day 1.
Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
38 15PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 35 others
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Mar 12, 2026 at 12:27 AM#8
Adding my data to this GLP-1 and beta-cell discussion:
| Metric | Baseline | Month 5 | Month 8 |
|---|---|---|---|
| Weight | 278 lbs | 228 lbs | 203 lbs |
| A1C | 7.2% | 6.0% | 5.4% |
| hsCRP | 7.0 | 4.0 | 1.2 |
Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.5g/kg/day.
Last edited: Mar 12, 2026 at 2:27 AM
12 15LibrarianMeg, bri_stats, pete_manc_UK and 9 others
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Shop Reference StandardsMar 12, 2026 at 12:44 AM#9
+1 to Dr.MetabolicMD. Especially the point about "Thank you all for the thoughtful replies..." — I have seen the same in my own experience with GLP-1 and beta-cell.
24 23sarah_TO, wendy_avl, jason_paloalto and 21 others
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Mar 12, 2026 at 1:01 AM#10
Slightly tangential to GLP-1 and beta-cell but mia_MS2 reminded me — has anyone else noticed changes in their alcohol tolerance?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
33 23cory_ATX, lori_vegas, Dr.PulmRoch and 30 others
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