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Bacteriostatic water sourcing guide — my results so far

MASHdoc_SA Sat, Aug 23, 2025 at 6:19 AM 29 replies 1,414 viewsPage 1 of 6
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MASHdoc_SA
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456
2,345
Aug 2024
San Antonio, TX
Aug 23, 2025 at 7:44 AM#1
I've been maintaining a spreadsheet of all community-submitted QSC testing results. Sharing the latest compilation here. ALL results below are from Janoshik unless otherwise noted. Only including consumer-submitted tests (not vendor-submitted). ## TIRZEPATIDE (56 tests compiled) | Batch | Date Tested | Purity | Tester | |-------|-------------|--------|--------| | TZ-2025-0847 | May 2025 | 97.1% | User: MidwestPep | | TZ-2025-0903 | Jun 2025 | 98.3% | User: LabRatLisa | | TZ-2025-0955 | Jul 2025 | 96.2% | User: ChemCheck | | TZ-2025-1022 | Aug 2025 | 97.8% | User: PurityPatrol | | TZ-2025-1089 | Sep 2025 | 93.1% | User: AZResearch ⚠️ | | TZ-2025-1105 | Oct 2025 | 98.9% | User: SoCal_Science | | TZ-2025-1189 | Nov 2025 | 98.7% | User: LabRatLisa | | TZ-2025-1204 | Dec 2025 | 97.4% | User: DataDrivenDave | | TZ-2026-0015 | Jan 2026 | 97.9% | User: EastCoastEndo | | TZ-2026-0088 | Feb 2026 | 98.1% | User: PeptidePioneer88 | *(showing 10 of 56 — full spreadsheet linked in my profile)* Tirz Summary Stats: - Mean: 97.3% | Median: 97.6% | Std Dev: 1.4% - Min: 93.1% | Max: 99.2% - Results ≥96%: 52/56 (92.9%) ## SEMAGLUTIDE (28 tests compiled) Sema Summary Stats: - Mean: 95.8% | Median: 96.1% | Std Dev: 1.9% - Min: 91.4% | Max: 98.6% - Results ≥94%: 24/28 (85.7%) ## RETATRUTIDE (8 tests compiled) Reta Summary Stats: - Mean: 96.1% | Median: 96.4% | Std Dev: 1.7% - Min: 93.3% | Max: 98.2% Key takeaway: QSC tirzepatide is their strongest product by purity. Semaglutide runs about 1.5 points lower on average. Retatrutide is still a smaller sample size but looking solid. The one outlier (93.1% tirz) was investigated — buyer admitted the vial had been stored at room temperature for 3 months before testing. Likely degradation, not a manufacturing issue. 📊
21 19TirzTom, TrialTracker_MD, JennaRN and 18 others
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EndoResFellow
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456
2,345
Sep 2024
Baltimore, MD
Aug 23, 2025 at 8:01 AM#2
As someone who does data analysis professionally, I love this. A few observations: 1. The standard deviation of 1.4% on tirz is impressively tight. This suggests good manufacturing consistency. 2. 92.9% of tirz results ≥96% is a strong pass rate. 3. The sema being lower is interesting — semaglutide is a more complex molecule (39 amino acids vs tirzepatide's 39, but with a C18 fatty acid chain modification that's harder to synthesize cleanly). One suggestion: it would be valuable to track these over time to see if there's any trend (improving or declining quality). A simple scatter plot of purity vs. date would reveal a lot.
Last edited: Aug 23, 2025 at 10:01 AM
33 4TinaHashiRN, robert_kc, dan_philly and 30 others
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kim_atl_prep
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312
1,345
Aug 2024
Atlanta, GA
Aug 23, 2025 at 8:18 AM#3
Great suggestion Steve. I actually have that chart in my spreadsheet. The short answer is: slightly improving trend over time. The earliest 2025 tests averaged about 96.5% while Q1 2026 tests average 97.8%. Small improvement but consistent. Suggests QSC is refining their synthesis process or at least maintaining quality as they scale. No concerning downward trends at all.
31 9RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 28 others
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PharmD_Rodriguez
Senior Member
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14,567
Jan 2024
Miami, FL
Aug 23, 2025 at 8:35 AM#4
This is phenomenal community science. A few things I want to highlight for newcomers: 1. These numbers beat many compounding pharmacies. The FDA has found compounded semaglutide testing as low as 40-60% at some pharmacies. QSC's worst result (91.4% sema) still crushes that. 2. Janoshik is the gold standard for peptide testing in this community. They're an accredited Czech lab. A Janoshik HPLC result is as reliable as it gets without pharmaceutical-level validation. 3. Consumer-submitted tests are more trustworthy than vendor-submitted because the vendor can't cherry-pick their best batch. Dave's compilation only using consumer tests is the right methodology. Thank you for maintaining this Dave. This is genuinely important harm reduction work. 🙌
Last edited: Aug 23, 2025 at 1:35 PM
44 3dan_philly, MeganSA_TX, LarryQC_SD and 41 others
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lisa_labSD
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278
1,234
Oct 2024
San Diego, CA
Aug 23, 2025 at 8:52 AM#5
I appreciate the data but want to push back on one thing: we're only testing for purity and identity. We're NOT testing for: - Endotoxin levels (bacterial contamination markers) - Residual solvents from synthesis - Heavy metals - Sterility - Particulate matter Purity ≠ safety. A vial could be 99% pure tirzepatide and still have dangerous levels of endotoxin. I'm not saying QSC products are unsafe — I use them myself — but let's not let high purity numbers create a false sense of complete safety. The full picture requires testing that costs $500+ per vial, which is why almost nobody does it.
4 11cory_ATX, lori_vegas, Dr.PulmRoch and 1 other
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