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ForumsDosing & ProtocolsDose escalation too fast? Recognizing over-titration symptoms — what worked for you? Page 3

Dose escalation too fast? Recognizing over-titration symptoms — what worked for you?

Dr.LipidDallas Wed, Jul 9, 2025 at 1:18 PM 15 replies 1,365 viewsPage 3 of 3
Dr.PainCLE
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Jul 9, 2025 at 5:33 PM#11
sarah.morrison said:
Dose escalation too fast

This is exactly right. sarah.morrison articulated what I have been trying to explain to my friends for months. The Dose escalation too fast? aspect is what made the difference for me.

Last edited: Jul 9, 2025 at 8:33 PM
38 13Dr.PathRoch, mona_PHX, andrew_nyc and 35 others
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Dr.PulmRoch
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Jul 9, 2025 at 5:50 PM#12

Reading this thread on Dose escalation too fast? hits close to home. Dad of 2 checking in — I started at 265 lbs and felt like I would tried everything.

11 months on tirz and I am a different person. Not just the 40 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Dose escalation too — take the leap. It was the best health decision I have ever made. ❤️

38 19traveltech_sara, AttorneyGrant, DebRD_ATL and 35 others
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DeniseRN_TPA
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Tampa, FL
Jul 9, 2025 at 6:07 PM#13

PharmHunterJen — that is really helpful context on Dose escalation too fast?. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

33 22tommy_boulder, hyun_seoul, jim_asheville and 30 others
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Dr.ObesityMed
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Jul 9, 2025 at 6:24 PM#14

To answer Dr.PulmRoch's question specifically:

From a clinical standpoint, Dose escalation too fast? is a reasonable concern that deserves a thorough answer.

The short answer: the evidence supports this approach for most patients.

The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.

14 6PeptideChemSF, A1cHero_PHX, Dr.RenalNash and 11 others
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CanadaChris
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Jul 9, 2025 at 6:41 PM#15

Bookmarked 📌 The Dose escalation too info in this thread is essential. Coming back to this for sure.

5 15lori_vegas, Dr.PulmRoch, maya_sedona and 2 others
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