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ForumsPharmacology & MechanismsSemaglutide albumin binding and the C-18 fatty acid linker — anyone have experience? Page 3

Semaglutide albumin binding and the C-18 fatty acid linker — anyone have experience?

cory_ATX Tue, Feb 3, 2026 at 1:07 AM 27 replies 1,145 viewsPage 3 of 6
jason_sac26
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Feb 3, 2026 at 5:22 AM#11

sean_dublin — wow. I've been looking for this exact info for weeks.

37 2pete_RVA, CarlaRPh_TPA, steph_laguna and 34 others
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Dr.LipidDallas
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Feb 3, 2026 at 5:39 AM#12

Slightly tangential to Semaglutide albumin but cory_ATX reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Feb 3, 2026 at 7:39 AM
2 5wei_SG, cory_ATX
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greg_boulder
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Boulder, CO
Feb 3, 2026 at 5:56 AM#13

Thanks for sharing this, cory_ATX. A few questions about your Semaglutide albumin experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Semaglutide?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Feb 3, 2026 at 7:56 AM
21 2Dr.DermMIA, fiona_VT, denise_HTX and 18 others
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cory_ATX
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Feb 3, 2026 at 6:13 AM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Semaglutide albumin.

To answer Dr.LipidDallas: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

47 0Dr.PathRoch, mona_PHX, andrew_nyc and 44 others
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BethLabQueen
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Virginia
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Feb 3, 2026 at 6:30 AM#15

Relevant to Semaglutide albumin binding — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 235 → 105 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Feb 3, 2026 at 7:30 AM
5 7wei_SG, cory_ATX, lori_vegas and 2 others
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