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ForumsDosing & ProtocolsHas anyone dealt with compounded sema dosing calculator? Page 2

Has anyone dealt with compounded sema dosing calculator?

AttorneyGrant Sun, Jun 15, 2025 at 10:50 AM 26 replies 1,412 viewsPage 2 of 6
Dr.ObesityLA
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Jun 15, 2025 at 1:40 PM#6

Quick practical note — if you're doing 0.125mg from a compounded vial, the reconstitution math matters a lot here. With a 5mg vial:

  • Add 2mL BAC water → 2.5mg/mL → 0.125mg = 0.05mL = 5 units

5 units on an insulin syringe is a very small amount — just be sure you're using a syringe with fine enough markings. A 0.3mL (30-unit) syringe will have individual unit markings and be much easier to read accurately at this volume than a full 1mL syringe.

50 3zoe_NC, Dr.ObesityLA, NurseKim_ATL and 47 others
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CarlaRPh_TPA
Senior Member
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Jun 15, 2025 at 1:57 PM#7

Great call on the syringe. I'll order the 0.3mL ones. Thank you for the advice! 🙏

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anna.melb_AU
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Jun 15, 2025 at 2:14 PM#8

Good discussion. I'll just add the standard disclaimer that micro-dosing is off-label and should be done under provider supervision. We don't want anyone reading this thread and deciding to start at a random low dose without medical guidance. Your provider can factor in your full medical history, not just your weight.

32 13emma_london, tammy_FL, Dr.LipidDallas and 29 others
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