TirzTom — that is really helpful context on Has anyone dealt with. Follow-up question: how long did you wait before increasing your dose?
I am in a similar situation (week 4) and trying to set realistic expectations.
To answer jim_asheville's question specifically:
From a clinical standpoint, Has anyone dealt with is a reasonable concern that deserves a thorough answer.
The short answer: the evidence supports this approach for most patients.
The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.
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View ResultsRelevant to Has anyone dealt with — here is my latest bloodwork comparison:
Key improvements: A1C 7.2% → 5.3%, triglycerides 235 → 105 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
Slightly tangential to Has anyone dealt with but Dr.EM_Chicago reminded me — has anyone else noticed changes in their alcohol tolerance?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.