Saving this for reference. Top-tier content.

Slightly tangential to When to hold at a dose vs but JessicaM_2024 reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

+1 to JessicaM_2024. Especially the point about "A few questions about your When to hold ..." — I have seen the same in my own experience with When to hold at a dose vs.

Dr.PeteFamMed — that is really helpful context on When to hold at a dose vs. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

To answer matt_MKE's question specifically:

From a clinical standpoint, When to hold at a dose vs is a reasonable concern that deserves a thorough answer.

The short answer: the evidence supports this approach for most patients.

The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.