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ForumsDosing & ProtocolsSplitting doses — 12 month update Page 5

Splitting doses — 12 month update

steph_laguna Wed, May 21, 2025 at 5:30 AM 24 replies 1,702 viewsPage 5 of 5
GenomicsKate
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Oct 2024
Cambridge, MA
May 21, 2025 at 12:35 PM#21

TirzTom — that is really helpful context on Splitting doses 12 month. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

17 19DebRD_ATL, KristenIndy, MarkLI_maint and 14 others
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HealthEcon_DC
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Apr 2024
Washington, DC
May 21, 2025 at 12:52 PM#22

Want to share my personal experience related to Splitting doses 12 month since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 260 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 10 months later: I am down 40 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Splitting doses 12 aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

Last edited: May 21, 2025 at 2:52 PM
40 22JessicaH_TX, KevinCompounds, TirzTom and 37 others
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Dr.EM_Chicago
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May 2024
Chicago, IL
May 21, 2025 at 1:09 PM#23

TirzTom — that is really helpful context on Splitting doses 12 month. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

Last edited: May 21, 2025 at 5:09 PM
49 7Dr.ReproEndo, lucas_SP_BR, lisa_labSD and 46 others
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Dr.LipidDallas
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Dec 2023
Dallas, TX
May 21, 2025 at 1:26 PM#24

Want to share my personal experience related to Splitting doses 12 month since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 277 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 16 months later: I am down 47 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Splitting doses 12 aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Last edited: May 21, 2025 at 3:26 PM
35 18lori_vegas, Dr.PulmRoch, maya_sedona and 32 others
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pam_stl
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Oct 2024
St. Louis, MO
May 21, 2025 at 1:43 PM#25

Just wanted to say — for anyone reading this Splitting doses 12 thread who is feeling discouraged: it gets better. The first month are the hardest. Hang in there. 💪

7 24RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 4 others
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