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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMetabolic Health & DiabetesGot off metformin for the first time in 8 years - crying happy tears Page 2

Got off metformin for the first time in 8 years - crying happy tears

MikeKY_noInsulin Mon, Feb 16, 2026 at 9:54 AM 20 replies 653 viewsPage 2 of 4
amy_econ_NJ
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May 2024
Princeton, NJ
Feb 16, 2026 at 12:44 PM#6

Subscribing to this thread. Got off metformin for the is exactly what I've been researching. 🙏

30 18Dr.SportsMedIN, amy_econ_NJ, bbq_ray_KC and 27 others
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MikeKY_noInsulin
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Oct 2024
Louisville, KY
Feb 16, 2026 at 1:01 PM#7

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Got off metformin for the.

To answer Dr.ObesityMed: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Feb 16, 2026 at 4:01 PM
19 13hannah_MT, Dr.SportsMedIN, amy_econ_NJ and 16 others
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DataDave
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Apr 2024
Washington
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Feb 16, 2026 at 1:18 PM#8

Adding my data to this Got off metformin for the discussion:

MetricBaselineMonth 4Month 8
Weight274 lbs234 lbs199 lbs
A1C6.8%6.2%5.4%
hsCRP8.03.00.8

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.

19 5LondonLisa, mike_nyc, VendorMark and 16 others
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DoseLogDan
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Feb 2025
Montana
Feb 16, 2026 at 1:35 PM#9

+1 to MikeKY_noInsulin. Especially the point about "Thank you all for the thoughtful replies..." — I have seen the same in my own experience with Got off metformin for the.

24 19sophie_paris, mel_PDX, Dr.AddMedPHL and 21 others
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LipidDoc_ATL
Senior Member
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Apr 2024
Atlanta, GA
Feb 16, 2026 at 1:52 PM#10

Slightly tangential to Got off metformin for the but carlos_SATX reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

32 8KristenIndy, MarkLI_maint, Dr.PeteFamMed and 29 others
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