OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on GLP-1R allosteric.
To answer Dr.GutHealth: my doctor and I discussed the options and went with brand.
Quick update: I have noticed more improvement since posting this. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
Adding my data to this GLP-1R allosteric discussion:
| Metric | Baseline | Month 4 | Month 6 |
|---|---|---|---|
| Weight | 268 lbs | 248 lbs | 223 lbs |
| A1C | 7.2% | 6.2% | 5.2% |
| hsCRP | 7.0 | 3.0 | 1.0 |
Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.5g/kg/day.
Janoshik Analytical — Independent Testing
Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.
Verify Your Peptides+1 to InsuranceTom. Especially the point about "Thank you all for the thoughtful replies..." — I have seen the same in my own experience with GLP-1R allosteric.
Slightly tangential to GLP-1R allosteric but pat_auckland reminded me — what is the latest on the oral formulations?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.