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ForumsDosing & ProtocolsSemaglutide 1.0mg for maintenance — 12 month update Page 6

Semaglutide 1.0mg for maintenance — 12 month update

Dr.Martinez Sun, Mar 9, 2025 at 11:53 AM 37 replies 1,986 viewsPage 6 of 8
Dr.Martinez
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Mar 9, 2025 at 8:23 PM#26

Congrats Dr.Martinez!! You should be so proud of yourself. 🎉

26 5AttorneyGrant, DebRD_ATL, KristenIndy and 23 others
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Dr.SportsMedIN
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Mar 9, 2025 at 8:40 PM#27

Slightly tangential to Semaglutide 1.0mg for but Admin reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Mar 10, 2025 at 1:40 AM
11 8lisa_labSD, adam_van, Dr.SurgeonPGH and 8 others
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RegAffairsDC
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Mar 9, 2025 at 8:57 PM#28

Yep. My endo said the same thing about Semaglutide 1.0mg.

47 20hannah_MT, Dr.SportsMedIN, amy_econ_NJ and 44 others
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dan_philly
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Mar 9, 2025 at 9:14 PM#29

Reading this thread on Semaglutide 1.0mg for hits close to home. Night shift nurse — I started at 283 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 58 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Semaglutide 1.0mg — take the leap. It was the best health decision I have ever made. ❤️

50 0Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 47 others
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Dr.EM_Chicago
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Mar 9, 2025 at 9:31 PM#30

As a pharmacist, I want to add some clinical context to this discussion on Semaglutide 1.0mg for maintenance 12.

Building on what RegAffairsDC said — the evidence base here is robust. The key publications to reference are from the FLOW program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
43 1lisa_labSD, adam_van, Dr.SurgeonPGH and 40 others
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