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ForumsPharmacology & MechanismsStructure-function of tirzepatide — my results so far Page 3

Structure-function of tirzepatide — my results so far

TomTeleRx Thu, Dec 4, 2025 at 6:08 AM 12 replies 930 viewsPage 3 of 3
pete_RVA
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Richmond, VA
Dec 4, 2025 at 10:23 AM#11

PurityPaulOR — wow. I've been looking for this exact info for weeks.

Last edited: Dec 4, 2025 at 3:23 PM
29 0mike_mod, SarahChen_PharmD, sarah.morrison and 26 others
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KristenIndy
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May 2024
Indianapolis, IN
Dec 4, 2025 at 10:40 AM#12

Slightly tangential to Structure-function of but TomTeleRx reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

45 17amsterdam_pete, LondonLisa, mike_nyc and 42 others
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KetoKyle
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Utah
Dec 4, 2025 at 10:57 AM#13

Thanks for sharing this, TomTeleRx. A few questions about your Structure-function experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about Structure-funct?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

33 18pat_auckland, Dr.GastroMayo, JakeBK_lifts and 30 others
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TomTeleRx
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Feb 2025
Delaware
Dec 4, 2025 at 11:14 AM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Structure-function of.

To answer KristenIndy: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

9 6HPLC_Greg, LibrarianMeg, bri_stats and 6 others
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VendorMark
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Dec 4, 2025 at 11:31 AM#15

Relevant to Structure-function of — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 231 → 101 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

16 13claudia_zurich, nancy_portland, rick_sfbay and 13 others
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