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ForumsMetabolic Health & DiabetesRemission of T2DM on GLP-1 — what worked for you? Page 3

Remission of T2DM on GLP-1 — what worked for you?

jim_asheville Mon, Jan 19, 2026 at 9:31 PM 29 replies 744 viewsPage 3 of 6
mike_mod
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Jan 20, 2026 at 1:46 AM#11

Moderator note: Please keep vendor-specific discussions in the Vendor Reviews section.

I have cleaned up a few off-topic posts. 👍

Last edited: Jan 20, 2026 at 3:46 AM
15 3PharmHunterJen, TomTeleRx, DoseLogDan and 12 others
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rachel_ABQ
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Jan 20, 2026 at 2:03 AM#12

As a healthcare provider, I want to add some clinical context to this discussion on Remission of T2DM on GLP-1 what worked.

Building on what jim_asheville said — the evidence base here is well-established. The key publications to reference are from the SELECT program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
Last edited: Jan 20, 2026 at 7:03 AM
22 18DadBodDave, AmyNC_wife, SkepticalSean and 19 others
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kate.chem
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Jan 20, 2026 at 2:20 AM#13
mike_mod said:
I have cleaned up a few off-topic posts

Gonna push back on this one. Remission of T2DM on GLP-1 what is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

28 10tyler_CSCS, VanRx_Mike, steve_okc and 25 others
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josh_phd_bmore
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Jan 20, 2026 at 2:37 AM#14

Want to share my personal experience related to Remission of T2DM on GLP-1 since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 285 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 10 months later: I am down 65 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Remission of T2DM on aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

30 7KarenAZ_mom, zoe_NC, Dr.ObesityLA and 27 others
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Dr.MetabolicMD
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Jan 20, 2026 at 2:54 AM#15

Saving this for reference. Quality thread.

33 13GenomicsKate, Dr.ObesityMed, HealthEcon_DC and 30 others
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