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ForumsDosing & ProtocolsMicro-dosing semaglutide — what worked for you? Page 2

Micro-dosing semaglutide — what worked for you?

Dr.NateNeph Wed, Nov 27, 2024 at 9:06 AM 18 replies 1,612 viewsPage 2 of 4
Dr.PeteFamMed
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Nov 27, 2024 at 11:56 AM#6

Quick practical note — if you're doing 0.125mg from a compounded vial, the reconstitution math matters a lot here. With a 5mg vial:

  • Add 2mL BAC water → 2.5mg/mL → 0.125mg = 0.05mL = 5 units

5 units on an insulin syringe is a very small amount — just be sure you're using a syringe with fine enough markings. A 0.3mL (30-unit) syringe will have individual unit markings and be much easier to read accurately at this volume than a full 1mL syringe.

37 11hyun_seoul, jim_asheville, matt_MKE and 34 others
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carlos_SATX
Member
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Oct 2024
San Antonio, TX
Nov 27, 2024 at 12:13 PM#7

Great call on the syringe. I'll order the 0.3mL ones. Thank you for the advice! 🙏

Last edited: Nov 27, 2024 at 2:13 PM
3 18FranDenver, Dr.BariatricHTX, LindaRN_retired
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Dr.ObesityLA
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Nov 27, 2024 at 12:30 PM#8

Good discussion. I'll just add the standard disclaimer that micro-dosing is off-label and should be done under provider supervision. We don't want anyone reading this thread and deciding to start at a random low dose without medical guidance. Your provider can factor in your full medical history, not just your weight.

Last edited: Nov 27, 2024 at 1:30 PM
39 8tampaLisa73, KarenAZ_mom, zoe_NC and 36 others
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