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ForumsOff-TopicCoffee and GLP-1 — has your caffeine tolerance changed? Page 2

Coffee and GLP-1 — has your caffeine tolerance changed?

NurseAsh_DET Wed, Mar 4, 2026 at 11:39 AM 8 replies 296 viewsPage 2 of 2
raj_cambridge
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Mar 4, 2026 at 2:29 PM#6

To answer the question about Coffee and GLP-1 has your caffeine tolerance changed? — in my experience this comes down to a few key factors.

I have been dealing with this for over a year now, and what I have found is that individual responses really do vary. That said, the general consensus on Coffee and GLP-1 has your seems solid.

What specifically worked for me: getting baseline labs before making any changes. I would suggest NurseAsh_DET try the same approach and reporting back.

33 18SleepFixSam, PurityPaulOR, MaxMetOK and 30 others
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nick_newbie
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Mar 4, 2026 at 2:46 PM#7

Yep. My endo said the same thing about Coffee and GLP-1 .

39 0dan_philly, MeganSA_TX, LarryQC_SD and 36 others
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VendorMark
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Mar 4, 2026 at 3:03 PM#8

Clinical perspective on Coffee and GLP-1 has your caffeine:

I have managed roughly 300 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

32 15MarkLI_maint, Dr.PeteFamMed, claudia_zurich and 29 others
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DeniseRN_TPA
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Mar 4, 2026 at 3:20 PM#9

To answer the question about Coffee and GLP-1 has your caffeine tolerance changed? — in my experience this comes down to a few key factors.

I have been dealing with this for almost 2 years now, and what I have found is that individual responses really do vary. That said, the general consensus on Coffee and GLP-1 has your seems solid.

What specifically worked for me: combining medication with structured exercise. I would suggest NurseAsh_DET try the same approach and reporting back.

42 13LindaRN_retired, tommy_boulder, hyun_seoul and 39 others
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mark_tokyo
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Tokyo, JP
Mar 4, 2026 at 3:37 PM#10

Reading this thread on Coffee and GLP-1 has hits close to home. Dad of 2 checking in — I started at 277 lbs and felt like I would tried everything.

13 months on tirz and I am a different person. Not just the 52 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Coffee and GLP-1 — take the leap. It was the best health decision I have ever made. ❤️

19 9TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 16 others
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