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ForumsPharmacology & MechanismsStructure-activity relationships of GLP-1 analogs — looking for input Page 3

Structure-activity relationships of GLP-1 analogs — looking for input

pat_auckland Thu, Oct 2, 2025 at 9:12 PM 11 replies 949 viewsPage 3 of 3
JennaRN
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Oct 3, 2025 at 1:27 AM#11

Yep. My endo said the same thing about Structure-activity.

Last edited: Oct 3, 2025 at 2:27 AM
7 22Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez and 4 others
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SleepFixSam
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Hawaii
Oct 3, 2025 at 1:44 AM#12

Reading this thread on Structure-activity hits close to home. Night shift nurse — I started at 271 lbs and felt like I would tried everything.

7 months on tirz and I am a different person. Not just the 46 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Structure-activity — take the leap. It was the best health decision I have ever made. ❤️

2 9ingrid_STO, pete_nash
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Admin
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Oct 3, 2025 at 2:01 AM#13

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

42 9RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 39 others
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labquiet_amy
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Oct 3, 2025 at 2:18 AM#14

Relevant to Structure-activity — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 203 → 103 mg/dL, hsCRP 6.0 → 0.9 mg/L. All on tirzepatide for 7 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

29 2bri_stats, pete_manc_UK, anna.melb_AU and 26 others
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matt_MKE
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Milwaukee, WI
Oct 3, 2025 at 2:35 AM#15

Congrats JennaRN!! Keep going — you're doing incredible. 🎉

33 22DanielChem_CHI, marco_milano, pam_columbus and 30 others
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