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ForumsMetabolic Health & DiabetesGLP-1 and gluconeogenesis — my results so far Page 2

GLP-1 and gluconeogenesis — my results so far

carlos_SATX Sat, Dec 13, 2025 at 7:15 AM 11 replies 875 viewsPage 2 of 3
SleepDoc_PDX
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Sep 2024
Portland, OR
Dec 13, 2025 at 10:05 AM#6

Congrats carlos_SATX!! Keep going — you're doing incredible. 🎉

44 7pete_nash, hank_denver, carlos_SATX and 41 others
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jim_asheville
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Aug 2024
Asheville, NC
Dec 13, 2025 at 10:22 AM#7

Clinical perspective on GLP-1 and gluconeogenesis my results so:

I have managed roughly 300 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

15 18BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 12 others
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LondonLisa
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Mar 2024
London, UK
Dec 13, 2025 at 10:39 AM#8

+1. This mirrors my journey exactly. The GLP-1 and gluconeoge discussion here is so valuable.

31 8RetaRick_CA, JenPlateau, SallyK_inj and 28 others
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hyun_seoul
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Jul 2024
Seoul, KR
Dec 13, 2025 at 10:56 AM#9

Reading this thread on GLP-1 and gluconeogenesis hits close to home. Dad of 2 checking in — I started at 297 lbs and felt like I would tried everything.

13 months on tirz and I am a different person. Not just the 72 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about GLP-1 and gluconeoge — take the leap. It was the best health decision I have ever made. ❤️

23 24BariatricNurseD, MASHdoc_SA, GenomicsKate and 20 others
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Dr.NephBHM_UK
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Jun 2024
Birmingham, UK
Dec 13, 2025 at 11:13 AM#10
SleepDoc_PDX said:
Keep going — you're doing incredible

This is exactly right. SleepDoc_PDX articulated what I have been trying to explain to my doctor for months. The GLP-1 and gluconeogenesis aspect is the most important factor.

Last edited: Dec 13, 2025 at 5:13 PM
43 23PeptideChemSF, A1cHero_PHX, Dr.RenalNash and 40 others
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