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ForumsMetabolic Health & DiabetesMy A1C dropped so fast my doctor thought the lab made an error — looking for input Page 4

My A1C dropped so fast my doctor thought the lab made an error — looking for input

MikeNYC_runner Fri, Nov 28, 2025 at 12:45 PM 39 replies 1,190 viewsPage 4 of 8
MikeNYC_runner
Member
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Jul 2024
New York, NY
Nov 28, 2025 at 6:25 PM#16

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on My A1C dropped so fast my.

To answer TirzTom: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

45 8PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 42 others
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labquiet_amy
Senior Member
1,234
6,789
Mar 2024
Cambridge, MA
Nov 28, 2025 at 6:42 PM#17

Relevant to My A1C dropped so fast my — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 241 → 111 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

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pete_nash
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1,345
Aug 2024
Nashville, TN
Nov 28, 2025 at 6:59 PM#18

100%. My provider said the same thing about My A1C dropped so.

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MikeFit_NJ
Senior Member
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6,543
Apr 2024
New Jersey
Nov 28, 2025 at 7:16 PM#19

Slightly tangential to My A1C dropped so fast my but raj_cambridge reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

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TomTeleRx
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Feb 2025
Delaware
Nov 28, 2025 at 7:33 PM#20
MikeNYC_runner said:
Thank you all for the thoughtful replies on My A1C dropped so fast my

This is exactly right. MikeNYC_runner articulated what I have been trying to explain to my doctor for months. The My A1C dropped so fast my aspect is the most important factor.

32 6TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 29 others
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