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ForumsMetabolic Health & DiabetesMy A1C dropped so fast my doctor thought the lab made an error — looking for input Page 5

My A1C dropped so fast my doctor thought the lab made an error — looking for input

MikeNYC_runner Fri, Nov 28, 2025 at 12:45 PM 39 replies 1,190 viewsPage 5 of 8
julia.endo
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Cincinnati, OH
Nov 28, 2025 at 7:50 PM#21

Just wanted to say — for anyone reading this My A1C dropped so thread who is feeling discouraged: it gets better. The first few weeks are the hardest. Hang in there. 💪

22 6anna.melb_AU, mark_tokyo, hans_munich and 19 others
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jennifer_SEA
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Seattle, WA
Nov 28, 2025 at 8:07 PM#22

Want to share my personal experience related to My A1C dropped so fast my since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 286 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 16 months later: I am down 71 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The My A1C dropped so aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Last edited: Nov 29, 2025 at 2:07 AM
10 10Dr.ReproEndo, lucas_SP_BR, lisa_labSD and 7 others
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VendorMark
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Jan 2024
Texas
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Nov 28, 2025 at 8:24 PM#23

Clinical perspective on My A1C dropped so fast my doctor thought:

I have managed ~150 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that the medication works best as part of a comprehensive approach.

For this specific question, I would recommend: getting comprehensive baseline labs first.

Last edited: Nov 28, 2025 at 10:24 PM
22 21MarkLI_maint, Dr.PeteFamMed, claudia_zurich and 19 others
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mike_mealprep
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Chicago, IL
Nov 28, 2025 at 8:41 PM#24

Thank you jennifer_SEA! This is incredibly helpful. Bookmarking for later. 🙏

25 19mel_PDX, Dr.AddMedPHL, newstart_MO and 22 others
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FDA_TrackerJim
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Rockville, MD
Nov 28, 2025 at 8:58 PM#25

Relevant to My A1C dropped so fast my — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 249 → 119 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

39 4jason_paloalto, Dr.LeslieOBGYN, MikeNYC_runner and 36 others
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