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ForumsMetabolic Health & DiabetesPrediabetic and scared - will this actually prevent diabetes? — need advice Page 3

Prediabetic and scared - will this actually prevent diabetes? — need advice

JessicaH_TX Sun, Nov 23, 2025 at 8:37 AM 21 replies 910 viewsPage 3 of 5
mike_mod
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Nov 23, 2025 at 12:52 PM#11

Moderator note: This thread has been getting great engagement. Please remember to cite sources when making clinical claims.

No issues to report — carry on. 👍

40 20PharmHunterJen, TomTeleRx, DoseLogDan and 37 others
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BariatricNurseD
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Nov 23, 2025 at 1:09 PM#12

As a pharmacist, I want to add some clinical context to this discussion on Prediabetic and scared - will this.

Building on what JessicaH_TX said — the evidence base here is robust. The key publications to reference are from the SUSTAIN program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
49 15roxy_nash, tony_orlando, Dr.NephBHM_UK and 46 others
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LarryQC_SD
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Nov 23, 2025 at 1:26 PM#13
mike_mod said:
Please remember to cite sources when making clinical claims

Gonna push back on this one. Prediabetic and scared - will this is not that straightforward in my experience. I have been on this for 12 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But cost accessibility is a real barrier. We should be honest about that.

Last edited: Nov 23, 2025 at 2:26 PM
32 3TinaHashiRN, robert_kc, dan_philly and 29 others
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PeptideChemSF
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Nov 23, 2025 at 1:43 PM#14

Want to share my personal experience related to Prediabetic and scared - will since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 289 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 14 months later: I am down 49 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Prediabetic and aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

42 16ricardo_MIA, BrianDallas92, labquiet_amy and 39 others
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chris_chi24
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Nov 23, 2025 at 2:00 PM#15

Saving this for reference. Top-tier content.

38 16SleepFixSam, PurityPaulOR, MaxMetOK and 35 others
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