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ForumsPharmacology & MechanismsStructure-function of tirzepatide — what worked for you? Page 3

Structure-function of tirzepatide — what worked for you?

mel_PDX Wed, Jul 9, 2025 at 4:06 PM 13 replies 1,219 viewsPage 3 of 3
paige_pharma
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Sep 2024
Omaha, NE
Jul 9, 2025 at 8:21 PM#11

carlos_SATX — wow. I've been looking for this exact info for weeks.

46 18rachel_ABQ, traveltech_sara, AttorneyGrant and 43 others
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Dr.EndoIndy
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Oct 2024
Indianapolis, IN
Jul 9, 2025 at 8:38 PM#12

Slightly tangential to Structure-function of but mel_PDX reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

8 8LeilaHI, marcus_mpls, DeniseRN_TPA and 5 others
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BiostatsBrad
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Jul 2024
Durham, NC
Jul 9, 2025 at 8:55 PM#13

Thanks for sharing this, mel_PDX. A few questions about your Structure-function experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about Structure-funct?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

21 8FranDenver, Dr.BariatricHTX, LindaRN_retired and 18 others
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mel_PDX
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Dec 2024
Portland, OR
Jul 9, 2025 at 9:12 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Structure-function of.

To answer Dr.EndoIndy: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

15 4BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 12 others
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HPLC_Greg
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Research Triangle, NC
Jul 9, 2025 at 9:29 PM#15

Relevant to Structure-function of — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 231 → 101 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

1 20SaraMom3
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