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ForumsDosing & ProtocolsMath is hard - help me with reconstitution please — May 2025 Page 2

Math is hard - help me with reconstitution please — May 2025

TrialTracker_MD Mon, Feb 19, 2024 at 7:05 AM 10 replies 2,033 viewsPage 2 of 2
Dr.ObesityLA
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Dec 2023
Los Angeles, CA
Feb 19, 2024 at 9:55 AM#6

Wait I'm confused. My vial says 3mg not 5mg. Do I just use the same formula?

22 5zoe_NC, Dr.ObesityLA, NurseKim_ATL and 19 others
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FDA_TrackerJim
Senior Member
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Feb 2024
Rockville, MD
Feb 19, 2024 at 10:12 AM#7
Previously posted:
My vial says 3mg not 5mg. Do I just use the same formula?

Same exact formula, just different numbers. The universal formula is:

Volume to inject (mL) = Desired dose (mg) ÷ Concentration (mg/mL)

And concentration = Total mg in vial ÷ mL of BAC water added

So for your 3mg vial, if you add 1.5mL BAC water:

  • Concentration = 3mg / 1.5mL = 2mg/mL
  • 0.25mg dose = 0.25 / 2 = 0.125mL = 12.5 units (draw to halfway between 10 and 15)
  • 0.5mg dose = 0.5 / 2 = 0.25mL = 25 units

Or if you want easier numbers, add 1.2mL BAC water to get 2.5mg/mL, then 0.25mg = 10 units. Same as the 5mg vial example. The total number of doses per vial will be different of course (3mg total instead of 5mg).

18 22Admin, Dr.Martinez, mike_mod and 15 others
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ben_calgary
Member
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Oct 2024
Calgary, CA
Feb 19, 2024 at 10:29 AM#8

you are an absolute angel. I just did my first reconstitution and injection — 10 units, right in the belly, barely felt it. This community is the best. Thank you all so much!! 🙏🥹

28 20ZaraB_AL, JakeSmashed95, NauseaFreeNow and 25 others
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Dr.PathRoch
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Jun 2024
Rochester, MN
Feb 19, 2024 at 10:46 AM#9

Pinning this thread. We get this question at least twice a week. Excellent explanations as always from our knowledgeable members. For anyone reading this in the future, we also have a reconstitution calculator in the Tools section of the wiki.

And a reminder: always verify your math before injecting. If something seems off, ask here or call your provider. It's never a dumb question when it comes to dosing.

24 16SaraMom3, Dr.MetabolicMD, RetaRick_CA and 21 others
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