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ForumsMetabolic Health & DiabetesHOMA-IR tracking on GLP-1 — looking for input Page 3

HOMA-IR tracking on GLP-1 — looking for input

FDA_TrackerJim Sat, Aug 23, 2025 at 8:10 PM 41 replies 1,975 viewsPage 3 of 9
Admin
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Aug 24, 2025 at 12:25 AM#11

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

Last edited: Aug 24, 2025 at 4:25 AM
23 10PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 20 others
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CarlaRPh_TPA
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Aug 24, 2025 at 12:42 AM#12

Clinical perspective on HOMA-IR tracking on GLP-1 looking for:

I have managed roughly 300 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that the medication works best as part of a comprehensive approach.

For this specific question, I would recommend: getting comprehensive baseline labs first.

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KevinCompounds
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Aug 24, 2025 at 12:59 AM#13
Admin said:
Consult your healthcare provider

I respect Admin perspective but I think this oversimplifies things a bit. Re: HOMA-IR tracking on GLP-1 — the subgroup analyses show meaningful heterogeneity.

I am not saying Admin wrong entirely — just that the picture is more nuanced than a blanket statement. The STEP data specifically shows dose-dependent variation.

48 10MikeKY_noInsulin, Dr.RaviCardio, jennifer_SEA and 45 others
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A1cHero_PHX
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Aug 24, 2025 at 1:16 AM#14

Reading this thread on HOMA-IR tracking on GLP-1 hits close to home. Night shift nurse — I started at 279 lbs and felt like I would tried everything.

15 months on tirz and I am a different person. Not just the 54 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about HOMA-IR tracking on — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Aug 24, 2025 at 6:16 AM
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chris_chi24
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Aug 24, 2025 at 1:33 AM#15

Bookmarked 📌 The HOMA-IR tracking on info in this thread is essential. Coming back to this for sure.

Last edited: Aug 24, 2025 at 4:33 AM
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