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Evidence-based GLP-1 & peptide discussion since 2023
ForumsDosing & ProtocolsMy doctor says stay on 1mg but I feel like I need more — anyone have experience? Page 4

My doctor says stay on 1mg but I feel like I need more — anyone have experience?

AussieAnna Mon, Jan 8, 2024 at 3:35 PM 42 replies 2,345 viewsPage 4 of 9
AussieAnna
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Sydney, AU
Jan 8, 2024 at 9:15 PM#16

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on My doctor says stay on.

To answer ricardo_MIA: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Jan 8, 2024 at 10:15 PM
44 5TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 41 others
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NicoleRaleigh
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Aug 2024
Raleigh, NC
Jan 8, 2024 at 9:32 PM#17

Relevant to My doctor says stay on 1mg but — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 205 → 105 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

22 8MikeFit_NJ, InsuranceTom, WendyG_ATL and 19 others
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TrialNerd_Beth
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Bethesda, MD
Jan 8, 2024 at 9:49 PM#18

100%. My provider said the same thing about My doctor says stay.

40 5TomTeleRx, DoseLogDan, SleepFixSam and 37 others
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Dr.KarenChen
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Nov 2023
San Francisco, CA
Jan 8, 2024 at 10:06 PM#19

Slightly tangential to My doctor says stay on but RunnerRach reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Jan 9, 2024 at 4:06 AM
44 1mike.trainer_LA, sarah_nash92, FitDadDave and 41 others
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Dr.SurgeonPGH
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Mar 2024
Pittsburgh, PA
Jan 8, 2024 at 10:23 PM#20
AussieAnna said:
Thank you all for the thoughtful replies on My doctor says stay on

This is exactly right. AussieAnna articulated what I have been trying to explain to my doctor for months. The My doctor says stay on aspect is the most important factor.

34 20B12Beth, RickReta_CO, PharmHunterJen and 31 others
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