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ForumsOral GLP-1 AgonistsOral GLP-1 pipeline overview — all agents in development Page 4

Oral GLP-1 pipeline overview — all agents in development

TrialTracker_MD Fri, Dec 1, 2023 at 4:00 PM 237 replies 46,413 viewsPage 4 of 20
kevin_tulsa
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489
2,123
Jun 2024
Tulsa, OK
Dec 1, 2023 at 9:40 PM#16

Congrats Dr.PeteFamMed!! Keep going — you're doing incredible. 🎉 👏

1 21fiona_glasgow
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JenPlateau
Member
234
890
Nov 2024
Missouri
Dec 1, 2023 at 9:57 PM#17

Clinical perspective on Oral GLP-1 pipeline overview all agents:

I have managed over 200 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

Last edited: Dec 2, 2023 at 3:57 AM
42 15TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 39 others
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PurityPaulOR
Senior Member
1,890
7,890
Mar 2024
Oregon
Dec 1, 2023 at 10:14 PM#18
kevin_tulsa said:
Keep going — you're doing incredible

I respect kevin_tulsa perspective but I think this oversimplifies things a bit. Re: Oral GLP-1 pipeline overview — the effect size varies considerably by population.

I am not saying kevin_tulsa wrong entirely — just that the picture is more nuanced than a blanket statement. The SUSTAIN data specifically shows different outcomes in different metabolic phenotypes.

13 23Admin, Dr.Martinez, mike_mod and 10 others
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MikeNYC_runner
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378
1,678
Jul 2024
New York, NY
Dec 1, 2023 at 10:31 PM#19

Can confirm — identical experience.

Last edited: Dec 2, 2023 at 12:31 AM
32 9GenomicsKate, Dr.ObesityMed, HealthEcon_DC and 29 others
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KetoKyle
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678
3,456
Jul 2024
Utah
Dec 1, 2023 at 10:48 PM#20

Want to share my personal experience related to Oral GLP-1 pipeline overview since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 255 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 14 months later: I am down 70 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Oral GLP-1 pipeline aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

11 7JakeBK_lifts, DerekSJ_a1c, paige_pharma and 8 others
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