🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsOral semaglutide 50mg (Rybelsus HD) — OASIS program results Page 3

Oral semaglutide 50mg (Rybelsus HD) — OASIS program results

Dr.Martinez Fri, Mar 13, 2026 at 7:03 AM 12 replies 196 viewsPage 3 of 3
Admin
Administrator
2,456
9,812
Oct 2023
Online
Mar 13, 2026 at 11:18 AM#11

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

Last edited: Mar 13, 2026 at 3:18 PM
38 22PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 35 others
Reply Quote Save Share Report
Dr.NutriCornell
Senior Member
1,345
6,234
Mar 2024
Ithaca, NY
Mar 13, 2026 at 11:35 AM#12

Slightly tangential to Oral semaglutide 50mg but Dr.ReproEndo reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

34 18Dr.SleepRoch, laura_annarbor, JenMemphis and 31 others
Reply Quote Save Share Report
TomTeleRx
Member
189
678
Feb 2025
Delaware
Mar 13, 2026 at 11:52 AM#13
tane_welly said:
Follow-up question: how long did you wait before increasing your dose

This is exactly right. tane_welly articulated what I have been trying to explain to my doctor for months. The Oral semaglutide 50mg aspect is the most important factor.

21 24LibrarianMeg, bri_stats, pete_manc_UK and 18 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides
JessicaM_2024
Member
823
3,456
Mar 2024
Portland, OR
Mar 13, 2026 at 12:09 PM#14

Saving this for reference. Top-tier content.

Last edited: Mar 13, 2026 at 1:09 PM
36 13Dr.PainCLE, mike_mealprep, NicoleRaleigh and 33 others
Reply Quote Save Share Report
dan_philly
Member
456
2,123
Jul 2024
Philadelphia, PA
Mar 13, 2026 at 12:26 PM#15

Adding my data to this Oral semaglutide 50mg discussion:

MetricBaselineMonth 5Month 8
Weight262 lbs217 lbs197 lbs
A1C6.6%6.0%5.4%
hsCRP6.04.01.2

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.

Last edited: Mar 13, 2026 at 3:26 PM
16 1EndoResFellow, PharmacoVig_BOS, SurmountFan_IN and 13 others
Reply Quote Save Share Report

Similar Threads

Orforglipron Phase 3 ATTAIN-1 topline — oral non-peptide GLP-116 replies
Danuglipron BID dosing — Pfizer oral GLP-1 update7 replies
Oral vs injectable GLP-1: bioavailability and efficacy comparison5 replies
Orforglipron food interaction profile — no fasting requirement15 replies
Oral sema absorption enhancer SNAC — how it works10 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register