🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsDosing & ProtocolsSemaglutide PK modeling — January 2024 Page 2

Semaglutide PK modeling — January 2024

PedsEndoPhilly Sun, Oct 29, 2023 at 6:01 PM 6 replies 2,062 viewsPage 2 of 2
RetaRick_CA
VIP Member
2,012
9,876
Jan 2024
California
Oct 29, 2023 at 8:51 PM#6

Quick practical note — if you're doing 0.125mg from a compounded vial, the reconstitution math matters a lot here. With a 5mg vial:

  • Add 2mL BAC water → 2.5mg/mL → 0.125mg = 0.05mL = 5 units

5 units on an insulin syringe is a very small amount — just be sure you're using a syringe with fine enough markings. A 0.3mL (30-unit) syringe will have individual unit markings and be much easier to read accurately at this volume than a full 1mL syringe.

Last edited: Oct 29, 2023 at 9:51 PM
46 18SkepticalSean, Dr.CardioMD, EndoResFellow and 43 others
Reply Quote Save Share Report
mike_nyc
VIP Member
5,678
21,345
Nov 2023
New York
Online
Oct 29, 2023 at 9:08 PM#7

Great call on the syringe. I'll order the 0.3mL ones. Thank you for the advice! 🙏

Last edited: Oct 30, 2023 at 1:08 AM
17 23stefan_berlin, Dr.EM_Chicago, pete_RVA and 14 others
Reply Quote Save Share Report
JessicaM_2024
Member
823
3,456
Mar 2024
Portland, OR
Oct 29, 2023 at 9:25 PM#8

Good discussion. I'll just add the standard disclaimer that micro-dosing is off-label and should be done under provider supervision. We don't want anyone reading this thread and deciding to start at a random low dose without medical guidance. Your provider can factor in your full medical history, not just your weight.

Last edited: Oct 29, 2023 at 10:25 PM
11 2mike_mealprep, NicoleRaleigh, james_edin and 8 others
Reply Quote Save Share Report

PeptideMeter — Independent Peptide Analytics

Community-driven peptide testing and vendor rating platform. Transparent results. Unbiased analysis. Trusted by thousands.

View Results

Similar Threads

Micro-dosing semaglutide — is sub-therapeutic dosing effective?16 replies
Injection technique: subcutaneous depot formation and absorption8 replies
Semaglutide PK modeling — when to time your injection12 replies
Reconstitution calculator — compounded peptide dosing math7 replies
Half-life implications for missed doses — PK-based guidance5 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register