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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMetabolic Health & DiabetesPrediabetic and scared - will this actually prevent diabetes? — looking for input

Prediabetic and scared - will this actually prevent diabetes? — looking for input

CarlaRPh_TPA Tue, Jun 24, 2025 at 1:13 AM 28 replies 1,671 viewsPage 1 of 6
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CarlaRPh_TPA
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Jun 24, 2025 at 2:38 AM#1

Okay I need help with this — prediabetic and scared - will this.

I have been dealing with this for weeks and I am getting frustrated. Googling just gives me contradictory information and my doctor does not seem to take it seriously.

Please tell me someone here has been through this and come out the other side. What did you do? What finally worked?

I know there are some really knowledgeable people on this forum so I am hoping someone can point me in the right direction. 😩

49 20FDA_TrackerJim, ricardo_MIA, BrianDallas92 and 46 others
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DanielChem_CHI
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Jun 24, 2025 at 2:55 AM#2
CarlaRPh_TPA said:
Prediabetic and scared - will this actually prevent diabetes? looking for input

Gonna push back on this one. Prediabetic and scared - will this is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

14 21Dr.DermMIA, fiona_VT, denise_HTX and 11 others
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maya_sedona
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Jun 24, 2025 at 3:12 AM#3
CarlaRPh_TPA said:
Prediabetic and scared - will this actually prevent diabetes? looking for input

This is exactly right. CarlaRPh_TPA articulated what I have been trying to explain to my friends for months. The Prediabetic and scared - aspect is what made the difference for me.

9 7BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 6 others
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LibrarianMeg
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Jun 24, 2025 at 3:29 AM#4

Clinical perspective on Prediabetic and scared - will this:

I have managed ~150 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that the medication works best as part of a comprehensive approach.

For this specific question, I would recommend: getting comprehensive baseline labs first.

Last edited: Jun 24, 2025 at 5:29 AM
33 13JessicaM_2024, TomFromTexas, mike.trainer_LA and 30 others
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RetaRick_CA
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Jun 24, 2025 at 3:46 AM#5
maya_sedona said:
looking for inputThis is exactly right

I respect maya_sedona perspective but I think this oversimplifies things a bit. Re: Prediabetic and scared - will — the subgroup analyses show meaningful heterogeneity.

I am not saying maya_sedona wrong entirely — just that the picture is more nuanced than a blanket statement. The SURMOUNT data specifically shows baseline BMI-dependent responses.

Last edited: Jun 24, 2025 at 4:46 AM
13 12MounjBrad, nick_newbie, DadBodDave and 10 others
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